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STEP 1: SELECT YOUR DISCOUNT PACKAGE

Congratulations on taking the first step; now comes the most important stage, in which you will choose the protocol that is most important for your current situation.

Average Customer Rating 4.9

4.9/5 (1612 Reviews)

Total Renew — Advanced Joint Relief Protocol

Deep-penetrating formula

Triple-action technology

Clinically-tested actives

Non-greasy, odor-free

Free Worldwide Shipping

on orders over $60

90-Day Money Back Guarantee

Satisfaction guaranteed

WARNING: Low Stock Notice

This product sold out 12 times last year. We encourage you to take advantage of the limited sale and buy now. Subscribing protects you against future stock outs.

PS: Only available here, don’t buy fakes on Amazon/eBay

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Don't Take Our Word For It

Join 22,500+ People Who Finally Found Relief

For three years, I used a walker just to get from the bedroom to the kitchen. Six weeks into Total Renew, I realized the walker was still against the wall — and I'd completely forgotten about it. On my daughter's wedding day, I took her arm and walked her down that aisle without thinking about my knees once.

Robert M., 67

Verified Buyer

For seven years, my husband Hank knelt in front of me every morning to put on my shoes. He never complained. But every time, something inside me broke a little. In week five of Total Renew, I bent down and did it myself — no pain, no help. It wasn't about the shoes. It was about my dignity.

Gloria T., 62

Verified Buyer

When arthritis took my fingers, I couldn't hold a screwdriver or button my own shirt. After seven weeks of applying Total Renew, I sat at my workbench and repaired two watches in the same week. My hands are back. And honestly, so am I.

Arthur B., 73

Verified Buyer

I used to make excuses every time Sophie asked me to play outside. I had a knee replacement scheduled and I was terrified. Six weeks into Total Renew, I canceled the surgery. Eight weeks in, I pushed her on those swings until my arms got tired — not my knees.

Linda W., 68

Verified Buyer

Clinically-Studied Ingredients

Backed by 100+ Scientific Studies on Joint and Muscle Pain

Stops the Destruction Before It Goes Any Further

Most treatments only mask the problem while the real one continues. Total Renew was created with clinically tested ingredients to act directly on the microscopic enzymes that destroy cartilage, silencing the signal that induces them to attack. The cycle of destruction that has been occurring within your joints for years finally ceases. Not temporarily. At the root of the problem.

Restores Natural Joint Lubrication

Chronic inflammation depletes the synovial fluid that keeps your joints moving smoothly. Without it, every step feels like rubbing bones together. Total Renew works to create a comfortable environment to replenish the key components of this fluid directly in the joint, so that friction and stiffness gradually give way to the smooth, fluid movement your joints were designed for.

Rebuilds What Was Lost — From the Outside In

Standard creams stop at the surface. Total Renew uses a deep-penetrating delivery system formulated to carry clinically-studied compounds through the skin and into the joint area — no detour through the stomach, no absorption loss. Straight to where the support is wanted.

Protection That Lasts Beyond the Bottle

The full 6-month protocol gives your routine the time it needs — not a 20-minute distraction. Most customers find that once they finish it, a simple maintenance routine keeps them feeling great. The comfort you build is real. And it doesn't disappear when you stop.

   Nature’s Best in Balance   

Pure and natural ingredients:

Melittin (Bee Venom Extract)

The cornerstone of the formula. Research from Washington University in St. Louis explored how Melittin, applied topically, penetrates through the skin to reach joint tissue — where studies have examined its potential interaction with the inflammatory signaling associated with cartilage-related enzymes (MMPs). Most companies won't touch it because it's expensive and difficult to source. We built our entire formula around it.

Boswellia Serrata

Featured in research published in the Indian Journal of Pharmaceutical Sciences, Boswellia has been studied for its interaction with the same inflammatory pathways researchers associate with joint discomfort. It works alongside Melittin to support a calm, comfortable feeling around the joint area.

Hyaluronic Acid 

Standard hyaluronic acid sits on the skin's surface and never reaches the joint area. The low-molecular-weight version we use is small enough to actually penetrate where it can do the most good — designed to support the natural fluid environment around the joint. Less grinding. More glide.

Apigenin (from Chamomile)

A flavonoid naturally found in chamomile that researchers have studied for its interaction with MMP-3 and MMP-13 — enzymes the body produces during periods of joint inflammation. A clinical paper from the University of Medical Sciences in Shiraz documented meaningful comfort improvements and better mobility with topical chamomile use on stiff knees.

Type II Collagen

Formulated at a molecular weight specifically designed to be absorbed through the skin. Clinical research at Harvard Medical School has explored this form of collagen and how the body's signaling responds to it — a key reason it's part of our long-term protocol.

90-DAY MONEY-BACK GUARANTEE

Give it three full months. Apply it, feel the difference, and decide for yourself. If you don't experience a meaningful improvement in pain, stiffness, and mobility — for any reason — contact our team and we'll refund every dollar. No questions. No hoops. You don't even need to return the jars. The risk is entirely ours.

FAQ

How is Total Renew different from other joint creams I've tried before?

Give it three full months. Apply it, feel the difference, and decide for yourself. If you don't experience a meaningful improvement in pain, stiffness, and mobility — for any reason — contact our team and we'll refund every dollar. No questions. No hoops. You don't even need to return the jars. The risk is entirely ours.

I'm 75 years old. Is my condition too advanced for this to work?

Not even close. Total Renew is designed for adults of every age looking to support their joint comfort and daily mobility — and some of our happiest customers are in their 70s and 80s. The formula is gentle enough for daily use and works best when applied consistently throughout the full 6-month protocol. Age is not the obstacle people think it is.

Can I take Total Renew with other supplements or medications?

Total Renew is a topical cream made with natural ingredients, so it's generally easy to incorporate alongside other wellness products. That said, if you're managing a medical condition or taking prescription medication, we always recommend a quick chat with your healthcare provider before adding anything new to your routine

How much should I order?

Honestly? As much as you can. The full protocol is six months for a real reason — supporting joint comfort and mobility takes consistency, and customers who go all-in on the 6-jar package are the ones who write us the kinds of stories you read above. The per-jar price drops significantly, shipping is free, and you're protected by the 90-day guarantee. If you'd rather try it first, the 2-jar option is a good place to start — but re-orders aren't guaranteed at today's discount.

How soon will I start to feel results?

Every body is different, but most customers tell us they start noticing how their joints feel within the first few weeks. Some feel it sooner. The full six-month protocol is designed to give your routine the time it needs to make a real, lasting difference — not just a quick win.

How long does shipping take?

Delivery times vary depending on your location. For the United States, delivery generally takes 10 to 15 business days. For other countries, it can range from 10 to 20 business days, depending on the region. Once your order is dispatched from NatureOne Lab facilities, you will receive a tracking code via email and SMS to track the delivery in real time to your door.

Can I use Total Renew on multiple joints at the same time?

Absolutely. Many customers apply Total Renew to knees, hands, shoulders, hips, and lower back — wherever they want a little extra comfort. A small amount goes a long way, so a single jar covers more ground than you'd expect.

Is there anyone who should NOT use Total Renew?

Total Renew is made with natural ingredients and is well-tolerated by most adults. However, if you're allergic to bee products, pregnant, nursing, or managing a medical condition, please consult a qualified healthcare professional before use.

What if it doesn't work for me?

Then you don't pay for it. Contact our team within 90 days and we'll refund every dollar — and you keep the jars. The risk is entirely ours. Always has been.

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Free Worldwide Shipping on orders over $60

Full Refund

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Secure Online Payment

Technology used by major banks

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The statements on this website have not been evaluated by the FDA and our products are not intended to diagnose, treat, cure, or prevent any disease. Individual results will vary. The information provided is for educational purposes only and should not replace medical advice — please consult a qualified healthcare professional before use, especially if pregnant, nursing, taking medication, or managing a medical condition.

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