Name: Total Renew - Advanced Joint & Muscle Relief Cream
Brand: TotalRenew
Price: 47.0 USD
Availability: InStock

22,500+ Happy Customers

4.9/5 (1612+ Reviews)

90 Day Guarantee

4.9/5 (1612 Reviews)

Total Renew — Advanced Joint Relief Protocol

Deep-penetrating formula

Triple-action technology

Clinically-tested actives

Non-greasy, odor-free

Free Worldwide Shipping

on orders over $60

90-Day Money Back Guarantee

Satisfaction guaranteed

WARNING: Low Stock Notice

This product sold out 12 times last year. We encourage you to take advantage of the limited sale and buy now. Subscribing protects you against future stock outs.

PS: Only available here, don’t buy fakes on Amazon/eBay

As Seen On:

Don't Take Our Word For It

Join 22,500+ People Who Finally Found Relief

For three years, I used a walker just to get from the bedroom to the kitchen. Six weeks into Total Renew, I realized the walker was still against the wall — and I'd completely forgotten about it. On my daughter's wedding day, I took her arm and walked her down that aisle without thinking about my knees once.

Robert M., 67

Verified Buyer

For seven years, my husband Hank knelt in front of me every morning to put on my shoes. He never complained. But every time, something inside me broke a little. In week five of Total Renew, I bent down and did it myself — no pain, no help. It wasn't about the shoes. It was about my dignity.

Gloria T., 62

Verified Buyer

When arthritis took my fingers, I couldn't hold a screwdriver or button my own shirt. After seven weeks of applying Total Renew, I sat at my workbench and repaired two watches in the same week. My hands are back. And honestly, so am I.

Arthur B., 73

Verified Buyer

I used to make excuses every time Sophie asked me to play outside. I had a knee replacement scheduled and I was terrified. Six weeks into Total Renew, I canceled the surgery. Eight weeks in, I pushed her on those swings until my arms got tired — not my knees.

Linda W., 68

Verified Buyer

Clinically-Studied Ingredients

Backed by 100+ Studies on Joint Comfort and Mobility

Designed to Address What Most Creams Miss

Most joint creams mute the sensation for an hour or two — but the underlying activity keeps going. Studies on enzymes like MMPs suggest these may play a role in how cartilage changes over time. That's why Total Renew was formulated around ingredients researchers have explored for their potential to support a calmer joint environment. Not a quick distraction. Real, daily support.

Supports That Smooth, Lubricated Feeling

Long-term inflammation is associated with depletion of the natural fluids that keep joints feeling smooth. Total Renew is formulated with low-molecular-weight Hyaluronic Acid — designed to be absorbed where standard hyaluronic acid never reaches. Less grinding. More glide. The way it should be.

Reaches the Joint Area From the Outside In

Standard creams stop at the surface. Total Renew uses a deep-penetrating delivery system formulated to carry clinically-studied compounds through the skin and into the joint area — no detour through the stomach, no absorption loss. Straight to where the support is wanted.

A Protocol That Lasts Beyond the Bottle

The full protocol gives your routine the time it needs — not a 20-minute distraction. Most customers find that once they finish it, a simple maintenance routine keeps them feeling great. The comfort you build is real. And it doesn't disappear when you stop.

They Tried Everything. Watch What Finally Worked

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Nature’s Best in Balance

Pure and natural ingredients:

Melittin (Bee Venom Extract)

The cornerstone of the formula. Research from Washington University in St. Louis explored how Melittin, applied topically, penetrates through the skin to reach joint tissue — where studies have examined its potential interaction with the inflammatory signaling associated with cartilage-related enzymes (MMPs). Most companies won't touch it because it's expensive and difficult to source. We built our entire formula around it.

Boswellia Serrata

Featured in research published in the Indian Journal of Pharmaceutical Sciences, Boswellia has been studied for its interaction with the same inflammatory pathways researchers associate with joint discomfort. It works alongside Melittin to support a calm, comfortable feeling around the joint area.

Hyaluronic Acid

Standard hyaluronic acid sits on the skin's surface and never reaches the joint area. The low-molecular-weight version we use is small enough to actually penetrate where it can do the most good — designed to support the natural fluid environment around the joint. Less grinding. More glide.

Apigenin (from Chamomile)

A flavonoid naturally found in chamomile that researchers have studied for its interaction with MMP-3 and MMP-13 — enzymes the body produces during periods of joint inflammation. A clinical paper from the University of Medical Sciences in Shiraz documented meaningful comfort improvements and better mobility with topical chamomile use on stiff knees.

Type II Collagen

Formulated at a molecular weight specifically designed to be absorbed through the skin. Clinical research at Harvard Medical School has explored this form of collagen and how the body's signaling responds to it — a key reason it's part of our long-term protocol.

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Most Creams Quit After 20 Minutes. Here's What 12 Weeks Builds.

Total Renew works on a different clock — under the surface, one week at a time. Here's the 12-week timeline customers describe most often.

1

Total Renew cream being massaged into a knee in warm natural light

Weeks 1–3 · Delivery

Reaches the Source

What's happening

The deep-penetrating delivery system carries the actives — led by Melittin — past the surface and into the joint area. No detour through the stomach. No greasy residue sitting on the skin.

What you may notice

It absorbs in seconds and disappears. No smell. By the end of the first weeks, many customers say the joint simply feels less tight — not numbed, just quieter.

2

Older woman sitting on the floor playing with her grandchildren

Weeks 4–6 · Calm

Calms the Environment

What's happening

Boswellia Serrata and Apigenin go to work on the inflammatory pathways researchers link to a restless joint environment — the same MMP activity most creams ignore entirely.

What you may notice

Morning stiffness that used to set the tone for the whole day starts to ease sooner. The first few steps out of bed stop being the hardest part.

Verified · Week 5

"My grandkids stopped asking me to get down on the floor with them — they'd glance at my knees first. Week five, I sat cross-legged on the rug and built a whole block city with them. I wasn't the grandma who watches anymore. I was the grandma who plays."

— Marlene K., 64 · Verified Buyer

3

Man walking comfortably outdoors without bracing

Weeks 6–9 · Glide

Restores the Glide

What's happening

Low-molecular-weight Hyaluronic Acid — small enough to actually reach where standard HA never does — supports the natural fluid environment around the joint. Less grinding. More glide.

What you may notice

This is the window where most stories turn. Movement you'd quietly stopped doing comes back — stairs, kneeling, a walk that doesn't end early.

Verified · Week 6

"I used to park as close to the store as I could and still dread the walk in. By week six I parked at the far end without thinking, crossed the whole lot, and realized halfway I'd forgotten to brace for it. I don't plan my days around walking distance anymore. I just go."

— Dennis P., 69 · Verified Buyer

4

Older woman fastening the buttons on her coat with steady hands

Weeks 9–12 · Renew

Builds Lasting Comfort

What's happening

Type II Collagen — formulated at a molecular weight designed to absorb through the skin — anchors the back half of the protocol. By week 12 the routine has had the time it needs to make a difference that holds.

What you may notice

The gains stop being a surprise and start being normal. Most customers shift to a simple maintenance routine from here and keep the ground they gained.

Verified · Week 8

"Buttons defeated me. My daughter had to do up my blouse like I was a child again. Eight weeks in, I fastened every button on my coat — and then I threaded a needle. My hands answer to me again. At 71, that's not a small thing. That's everything."

— Frances O., 71 · Verified Buyer

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90-DAY MONEY-BACK GUARANTEE

Here's the deal: Give Total Renew three full months. Apply it daily. Pay attention to how you feel.

If at the end of 90 days you're not genuinely happy with the difference — for any reason at all, or no reason — just send our team an email and we'll refund every dollar. No questions. No hoops. No "send the jars back" runaround.

You keep the jars. We send you the money. That's it.

We can offer that because we know what happens when people actually use Total Renew the way it was designed to be used. The risk is entirely ours. All you have to do is start.

Why 22,500+ People Swear By Total Renew

22,500+ customers, and the stories keep sounding the same. Here's a sample, unedited.

4.9 ★★★★★ Based on 1,612 reviews Rated Excellent

5 ★ 92%

4 ★ 6%

3 ★ 1%

2 ★ 1%

1 ★ 0%

★★★★★ Verified

Tried every cream at the pharmacy, none lasted more than an hour. This one's different. Took a few weeks but now I do the basement stairs with the laundry and don't even think about it.

Carol D., 66

★★★★★ Verified

My fingers wouldn't close around my coffee mug in the mornings. Been using it on my hands about a month now and I'm gripping the mug again. Doesn't smell either, which is a plus.

Wayne T., 71

★★★★★ Verified

Buddy and I do our whole morning loop again. Used to cut it in half cuz of my knees. Not anymore.

Pat S., 63

★★★★★ Verified

Shoulder had me asking my wife to reach the top shelf for years. Put it on every day, gave it time, and by month two I'm putting the plates away myself. Felt like getting something back.

Harold M., 74

★★★★★ Verified

Getting out of the car used to be a whole production. Now I just swing my legs out and go. Not greasy, no weird smell. Happy customer.

Janet R., 68

★★★★★ Verified

Gave up my garden two summers ago, my lower back couldn't take the kneeling. This spring I planted the whole row myself. Wish I'd found this stuff sooner honestly.

Bill K., 70

★★★★★ Verified

Told my husband I'd just watch at our anniversary. Ended up dancing the whole song. He didn't say anything, just held on. That says it all.

Donna F., 65

★★★★☆ Verified

Didn't feel much the first couple weeks and almost quit. Glad I stuck with it. Played a full 18 by week seven and woke up fine. Only knock is I wish it kicked in faster.

Eugene W., 72

★★★★★ Verified

My hands had quit on me. Finished a whole baby blanket for my granddaughter last week, first thing I've made in years. Works if you're consistent with it.

Sharon L., 69

FAQ

How is Total Renew different from other joint creams I've tried before?

Most joint creams rely on a cooling or warming sensation that fades in minutes — they're designed to distract you, not support you. Total Renew is built on a deep-penetrating delivery system and a clinically-studied blend of ingredients chosen specifically for joint comfort, mobility, and flexibility. It's a real protocol — not a quick trick. That's why people who've tried everything tell us Total Renew is finally something

I'm 75 years old. Is my condition too advanced for this to work?

Not even close. Total Renew is designed for adults of every age looking to support their joint comfort and daily mobility — and some of our happiest customers are in their 70s and 80s. The formula is gentle enough for daily use and works best when applied consistently throughout the full 6-month protocol. Age is not the obstacle people think it is.

Can I take Total Renew with other supplements or medications?

Total Renew is a topical cream made with natural ingredients, so it's generally easy to incorporate alongside other wellness products. That said, if you're managing a medical condition or taking prescription medication, we always recommend a quick chat with your healthcare provider before adding anything new to your routine

How much should I order?

Honestly? As much as you can. The full protocol is six months for a real reason — supporting joint comfort and mobility takes consistency, and customers who go all-in on the 6-jar package are the ones who write us the kinds of stories you read above. The per-jar price drops significantly, shipping is free, and you're protected by the 90-day guarantee. If you'd rather try it first, the 2-jar option is a good place to start — but re-orders aren't guaranteed at today's discount.

How soon will I start to feel results?

Every body is different, but most customers tell us they start noticing how their joints feel within the first few weeks. Some feel it sooner. The full six-month protocol is designed to give your routine the time it needs to make a real, lasting difference — not just a quick win.

How long does shipping take?

Delivery times vary depending on your location. For the United States, delivery generally takes 10 to 15 business days. For other countries, it can range from 10 to 20 business days, depending on the region. Once your order is dispatched from NatureOne Lab facilities, you will receive a tracking code via email and SMS to track the delivery in real time to your door.

Can I use Total Renew on multiple joints at the same time?

Absolutely. Many customers apply Total Renew to knees, hands, shoulders, hips, and lower back — wherever they want a little extra comfort. A small amount goes a long way, so a single jar covers more ground than you'd expect.

Is there anyone who should NOT use Total Renew?

Total Renew is made with natural ingredients and is well-tolerated by most adults. However, if you're allergic to bee products, pregnant, nursing, or managing a medical condition, please consult a qualified healthcare professional before use.

What if it doesn't work for me?

Then you don't pay for it. Contact our team within 90 days and we'll refund every dollar — and you keep the jars. The risk is entirely ours. Always has been.

CHOOSE YOUR PROTOCOL